Hesham's Notes: post #504 — TG.ME

📌 Random Medical Notes #10:
"Management of an Anaphylactic reaction to a drug":

- If an allergic reaction occurs:

📍ABCDE APPROACH for life-threatining problems,

keep the patient supine or semi-sitting, not standing, discontinue the drug administeration ..

📍1st line of TTT:
Give 0.5 mg Adrenaline I.M in the middle of the anterolateral part of the thigh ..

So, with Adrenaline 0.25 mg/ ml ampoule for example.. we give 2 ml I.M ..

to be repeated every 5 mins if symptoms didn't improve up to 2 doses ..

If no improvement, refer to the Refractory Anaphylaxis algorithm shown below ..

📍 Monitoring: NIBP, Pulse oximeter, ECG

📍+ if Hypotension occurs:
Administer IV Crystalloids (Normal Saline or Ringer lactate) via wide-bore cannula rapidly (Give 1 Liter bolus in adults, with additional fluid resuscitation as needed in severe anaphylactic shock up to 3-5 Liters in adults)

📍+ if Respiratory distress occurs:
Administer High flow Oxygen (6-8L/ min) + Nebulized Atrovent or Salbutamol in case of Wheezy chest

📍 Additional lines of TTT:
Give Dexa, Hydrocortisone, and Avil to relieve the allergic reaction symptoms ..

Transport the patient to hospital

The algorithm shown below may be of help..
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February 18, 2025 3.8K 18