Inverse agonists are druas which have an affinity for a receptor, but… — Pharmacology

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Inverse agonists are druas which have an affinity for a receptor, but the intrinsic activity opposite to that of an agonist. ◦ IA of an inverse agonist is between 0 and -1

The ability of the drug to bind with a receptor is called affinity. ◦ The capacity of a drug to induce a functional change in the receptor is called intrinsic activity or efficacy.

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