الدكتورة منية توضيحاً لشرحها (Gleason patterns and Gleason Scoring) for prostatic cancer اعد القراءة مرتين والفكرة رح توصل لك تماما Glandular structures microscopically prominent in grade 2- 3 (as in pattern 1 , 2 ,3 ) Papillary means more grade 3-4 (as in pattern 3-4) Solid to cribriform more grade grade 4 (as in pattern 4 ) Diffused and Comedo more grade 5 ( as in pattern 5 ) ( المقصد هي تشرح لنا على grading داخل الى Scoring نفسة ، كلما زاد ال grading زادت ال complexity pattern ) وبالأول والأخير نتيجتك النهائية تعتمد على ال Scoring وال Scoring رح يكون معاك احتمالين من كل pattern وبالتالي لو جمعت الاحتمالين من كل pattern رح يكون المجموع النهائي ( 10) وهذا هو ال Scoring ونبدأ ال Scoring من 2 , لانه دائما ال prostatic cancer يعمل involvement لأكثر من surgical lobes فأقل شئ احصل على 2 patterns فأقوم بجمعهم Sum of patterns from core biopsy (6 surgical lobes of prostate with each has specific pattern or no pattern ) leading to Gleason's scoring Scoring 2-4 = relatively low grade well differentiated and good prognosis Scoring 5-7 = relatively intermediate grade , moderately differentiated , intermediate prognosis Scoring 8- 10 = high grade cancer , poorly differentiated and bad prognosis
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