Insilico Medicine's rentosertib — where AI identified the target protein and designed the molecule in 18 months — showed treated patients looking 3–6 years biologically younger across six independent aging clocks after 12 weeks.
The trial was small (42 patients), short, and only in people with lung disease.
Treating sick lungs could itself shift the clocks without being a general anti-aging effect.
A cardiologist told the NYT the missing experiment is a trial in healthy people.
An AI-designed drug built for lung fibrosis appears to also reverse markers of biological aging.
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