However, has discussed in part one of the series, we do already have an understanding of safe levels, where no adverse events occur and we can let this be our guide as we continue to help people heal from disease. In conclusion, the literature strongly supports the concept of ROS-induced mitochondrial hormesis as a mechanism by which cells adapt to mild oxidative stress, leading to improved mitochondrial function, enhanced antioxidant defenses, and potential increases in healthspan and lifespan. Sources [1] Mitohormesis and metabolic health: The interplay between ROS ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718302/ [2] Hormesis and Oxidative Distress: Pathophysiology of Reactive ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405171/ [3] Exercise-Induced Mitohormesis for the Maintenance of Skeletal ... https://www.mdpi.com/2075-4663/7/7/170 [4] What is Mitohormesis? - News-Medical https://www.news-medical.net/life-sciences/What-is-Mitohormesis.aspx [5] Mitohormesis and metabolic health: The interplay between ROS ... https://www.sciencedirect.com/science/article/abs/pii/S0891584919306082
PubMed Central (PMC)Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuinsThe key role of mitochondria in oxidative metabolism and redox homeostasis explains the link between mitochondrial dysfunction and the development of metabolic disorders. Mitochond…
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