Dyslipidaemia and hepatic steatosis: mechanisms and implications for lipid-lowering therapy
https://www.nature.com/articles/s41569-026-01336-1
Nature Reviews Cardiology, Published online: 27 August 2026; doi:10.1038/s41569-026-01336-1 (https://www.nature.com/articles/s41569-026-01336-1)Dyslipidaemia and hepatic steatosis are interconnected disorders that contribute to the burden of cardiovascular disease. Understanding the interactions between lipoprotein metabolism, changes in circulating lipids and hepatic lipid accumulation is, therefore, essential for improving risk stratification and therapeutic strategies. In this Review, Averna and colleagues discuss mechanistic links between dyslipidaemia and hepatic steatosis, the clinical relevance of the balance between circulating lipids and hepatic lipid content and the effects of lipid-lowering therapies on hepatic steatosis.
2August 27, 2026 1.9K
